Overview
The AMD Integrative Biology Initiative aims to build on the AREDS2 clinical research study by correlating clinical AMD disease phenotypes with patient genotype and imaging information. Thanks to a partnership with the New York Stem Cell Foundation Research Institute (NYSCF), the Initiative is available to the vision research community and offers induced pluripotent stem cells (iPSCs) derived from participants with specific genetic risk factors.
Research Access
Application Requirements
To apply for access to the AMD Integrative Biology Initiative, please provide the following documents when requesting an account (Submit Here):
- Biographical Sketch (short version is encouraged), Curriculum Vitae, or Resume
- Research Proposal (three-page limit) including:
- Descriptive title
- Types of information being sought
- Detailed description of proposed project including timeline
- Data Management and Sharing Plan
- What data will you collect or create? What documentation and metadata will accompany the data?
- What tools, software, and/or code are required to access or manipulate the data?
- What standards will be applied to the data and metadata?
- How will you share the data? Are any restrictions on data sharing required?
- What data will be shared back with NEI after publication/final report?
- Who will be responsible for data management? What resources will you require?
- IRB Determination, if applicable
Data
Race Demographics
Ethnicity Demographics
Marital Status
Participants Gender
Age Distribution by Age
Notes
AREDS2 and iPSC lines data is controlled access and requires review of proposal by Data Access Committee (DAC). Upon approval from DAC, a Data User Agreement (DUA) is required.
Questions?
Please reach out to neiodshi@nei.nih.gov if you have questions about the AMD Integrative Biology Initiative.
