A Home for National Eye Institute
Supported Data and Resources

Data to scan for loci, genes, mutations/variations, phenotypes, other mammalian mutants and peer-reviewed publications associated with cataract. Links to the Entrez Gene and PubMed databases are provided.

Learn about the precise description of AMD disease pathobiology by using AMD genetic risk factors as sentinels for specific RPE signaling pathways and for changes in RPE physiology.

NEI has made the Ocular Proteome dataset available so that researchers can analyze protein changes related to genetic eye diseases. The dataset holds structures for over 100 proteins and over 1 million variants, cataloging the proteins atomic structures and stability generated by global computational mutagenesis.

Probe the relatedness and biological processes between the cornea, retina, RPE (choroid), and the rest of the human tissues by using a fully integrated dataset with differential expression, clustering, and GO term enrichment tools.