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Learn about the precise description of AMD disease pathobiology by using AMD genetic risk factors as sentinels for specific RPE signaling pathways and for changes in RPE physiology.
Probe the relatedness and biological processes between the cornea, retina, RPE (choroid), and the rest of the human tissues by using a fully integrated dataset with differential expression, clustering, and GO term enrichment tools.
Evaluate mutation severity using protein structures that are from protein databases or generated by homology modeling, refined by molecular dynamics, and mutated using global computational mutagenesis.
Learn about a clinical trial aimed to validate a survey tool that assesses visual symptoms both before and after LASIK surgery and to identify changes over a short period of time.